Ensemble
Casey Kasem
Shaggy Rogers (voice)
Frank Welker
Fred Jones / Scooby-Doo (voice)
Mindy Cohn
Velma Dinkley (voice)
Grey DeLisle
Daphne Blake / Natasha (voice)
Christine Baranski
Amelia von Butch (voice)
Ajay Naidu
Prince Omar (voice)
Ron Perlman
Hotep / Ancient One #2 (voice)
Jeremy Piven
Rock Rivers (voice)
Wynton Marsalis
Campbell (voice)
Oded Fehr
Amahl Ali Akbar (voice)
Virginia Madsen
Cleopatra (voice)